The activities of the Environmental and Health Research Group (EHRG) comprise investigation of various elements and compounds on different samples. Samples categories are biological samples, environmental samples, food samples and pharmaceutical samples. Biological samples are urine, blood, hair and nails from human. Environmental samples are water, different types of drinks and soft drinks, soils and air. Food samples are honey, milk, dairy products, and cereals such as rice, wheat, lintel, beans and others. Also, include different types of meat: beef, chicken, camel, goat, lamb and fish. Fruits are orange, banana, kiwi, mango and apple; while vegetables are watercress, onion, potatoes, tomato and others.
Different methods of analytical chemistry will be used to analysis the abovementioned samples. The classical methods are gravimetric analysis and volumetric titrations. The instrumental methods are UV/Vis spectrophotometry, IR spectroscopy and Inductively Coupled Plasma Mass Spectrometry (ICP-MS). Elements to be analyzed in different samples are copper (Cu), manganese (Mn), iron (Fe), lead (Pb), chromium (Cr), nickel (Ni), zinc (Zn), arsenic (As), selenium (Se), cobalt (Co) and others.
The main objective of the EHRG is to contribute in serving the local community and to raise the awareness about environment and health. Furthermore, is to support the right health policy and to consider preventive measurements to expose to contaminated foods and drinks. The data of the research activities will be published in national and international journals, also to disseminate the data widely to the community. We expect that the outcome of the EHRG to have national and international positive impact.
project name : Determination of Essential and Toxic Elements in different Foods Types
Summary : Foods quality can be affected by different conditions, which lead to contaminated foodstuff. Therefore, foods quality varies depending upon several factors. Location of farms, packing and transport will influence foods quality. Contaminated foods pose serious health problems to human health. Therefore, investigation of foods quality will help in a suitable utilization of different foods sources. The importance of this research is helping a community to consume good quality of foods. Moreover, this will help in decreasing health problems. The main goal is to enable people to consume good quality food. The limited of such study is a driving force behind this research to ease access to healthy foods. To make more database available for related authority to assess different foods types and their suitability for human consumption. Different methods of analytical chemistry will be used to analysis the food samples. The classical methods are gravimetric analysis and volumetric titrations. The instrumental methods are UV/Vis spectrophotometry, IR spectroscopy and Inductively coupled plasma mass spectrometry (ICP-MS). Elements to be analyzed in different samples are copper (Cu), manganese (Mn), iron (Fe), lead (Pb), chromium (Cr), nickel (Ni), zinc (Zn), arsenic (As), selenium (Se), cobalt (Co) and others.
Financial Support :
King Khalid University
Time Period: 2017–2018
Grant Number: R.G.P.1/7/38
Principal Investigator: Eid Ibrahim Brima
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project name : Detection of cytological changes in the Oral Mucosa among Local users of Tobacco in Najran in the KSA
Summary : This study was conducted in Najran city to detect the Cytological changes in the oral mucosa of tobacco users by applying AgNOR to determine the mean NOR counts. To use micronucleus assay to find micronuclei frequency per buccal cells. Also by using Papanicolaou stain method to detect the cytological atypical changes induced by Tobacco use and KI 67 as immunohistochemistry proliferation marker to confirm the change. This study is considered as an early screening program for pre-malignancy in oral mucosa. Early detection is possible for lesion caused by potential cancers. Therefore, this study aimed to assess the changes caused by tobacco use and to test the application of simple methods , cost-effective technologies, selective and specific in assessing the pre-cancer proliferative activity. Thirty to 80 percent of malignant tumors in the oral cavity lesions arising from pre-stage, such as leukoplakia, erythroplakia and fibrosis. The main objective of this study was to contribute in serving the local community and to raise the awareness about the hazard of using local tobacco (shemma). Moreover, is to help in formulating the right health policy as preventive measurements and to avoid any adverse health effects that can be caused by tobacco use. This study is on the line adopted by the Kingdom of Saudi Arabia through the Ministry of Health to warn about the dangers of tobacco and help to quit using it. The results of this study will serve in the same direction for health awareness and advice about the risks of tobacco.
Financial Support :
King Abdul-Aziz City for Sciences and Technology
Time Period: 2015–2017
Grant Number: AT-34-87
Principal Investigator: Eid Ibrahim Brima
- Brima, E. I., Harrington, C.F., Jenkins, R.O., Gault, A.G., Polya, D.A., Pearson, G. F., Greenway, G.M., Haris, P.I. Establishing a baseline value for urinary arsenic: selenium ratio in the unexposed population in the United Kingdom. Biomedical Spectroscopy and Imaging 2 (2013) 225–240.
- Brima, E. I., Abbas, A. M. Determination of Citric acid in Soft drinks, Juice drinks and Energy drinks using Titration. International Journal of Chemical Studies (2014), 1(6)30-34.
- Brima, E. I., Haris, P.I. Arsenic Removal from Drinking Water using Different Biomaterials and Evaluation of a Phytotechnology Based Filter. Res.J.chem.sci., 3(7),39-44(2014).
- Brima, E. I. Physicochemical properties and the concentration of anions, major and trace elements in groundwater, treated drinking water and bottled drinking water. Applied water Science (DOI 10.1007/s13201-014-0255-x, 2014) Appl Water Sci (2017) 7:401-410.
- Brima, E. I. Comparative study of the anions content between ground water, treated drinking water and bottled drinking water in Asir region. Journal of King Khalid University for Basic and Applied Sciences-JBAS.4 (2015)- 51–57.
- Brima, E. I. Determination of Metal Levels in Shamma (Smokeless Tobacco) with Inductively Coupled Plasma Mass Spectrometry (ICP-MS) in Najran, KSA. Asian Pacific Journal of Cancer Prevention. (2016). DOI:https://dx.doi.org/10.7314/APJCP.2016.17.10.XX.
- Brima, E. I. Detection of cytological changes in oral mucosa among users of smokeless tobacco (shamma) in the KSA. Diagnostic Cytopathology. 2017;1–7.
- A. A.Ateeg Determination of heavy metals contamination in fish flesh and water from the red sea coast of sudan-2013.
- Ismat. H. Ali and Ali. A. Ateegr, Kinetic and Mechanistic studies on Oxidation of Ethylenediamine-N,Nꞌ-diacetato Chromium(III) Complex by Peroiodate Ion in Aqueous Solutions.arab journal of physical chemistry2014.
- A.A. Ateeg, Ismat. H.Ali, Determination of mercury concentration in fish flesh of the red sea(Sudanese coast) by cold vapor atomic absorption aspectrometer,international journal of environmental science ,2015.
- Mohammed M. E1, Sharief Nawahil A2, Abukashawa Sumia, Mohamed O A3. Tamoxifen-induced lupus erythematosus. J Drug Metab Toxicol 2013, 4:1 https://dx.doi.org/10.4172/2157-7609.1000138.
- M.E.A. MOHAMMED, Ali ABEER, Fatima ELSAMANI, O.M. ELSHEIKH, Abdulrizak HODOW, O. Khamis HAJI. SIMULATION OF THE FATTY ACID SYNTHASE COMPLEX MECHANISM OF ACTION. Chemistry: Bulgarian Journal of Science Education 2013; 22 (3): 405- 412.
- Nuha M. Hassan1, Shawgi O. Harbi, Ahmed I. Shomo, Yassin I. Eltahir and Mohammed E. Ahamed. Cytokeratin 18 and vimentin expression in breast cancer tissues from Sudanese patients. Annals of Biological Research, 2014, 5 (1):9-16.
- Alkhansa Salih, Khalid Hussein Bakheat, Mohammed E A. Effect of FAC chemotherapy on plasma insulin concentration. IOSR-JPBS 2014, 9 (2): 71- 74.
- Mohammed E A Mohammed, Elsadig Mohamed Ahmed Fadlallah, Abdelrahim O Mohamed. Prolonged hyperglycemia in diabetic patients, its effect on inducing dyslipidemia and increasing the risk of cardiovascular disease. Int J Biol Med Res 2014; 5 (2): 3964- 3969.
- Mohammed Elimam Mohammed, Ammar Mohamed Hassan, Hala Ahmed Abdelhadi, Mohamed Gamaleldin Elsadig, Dalal Mohamed Adam, Khalid Elmamoun, Rania Hamid, Hiba Elias, Mohamed Abdallah, Zaki Abdelkarim, Nasr Eldin Elwali and Sulma Ibrahim Mohammed. Burden and Pattern of Cancer in the Sudan, 2000-2006. British Journal of Medicine & Medical Research ,2014 ; 4(5): 1231-1243.
- Asim Awad Mohammed Ahmed, Kannan Sanhouri, Hussain GadElkarim Ahmed , Riyadah Alamin, Husam Eldein Omer, A M Idris, Mutasim E Ibrahim, Mohammed E A Mohammed. Expression of EGFR, CK5 and CK19 in Oral Squamous Cell Carcinoma Tissues from Sudanese Patients. IJBRITISH 2014;1(4): 71- 75.
- Mohammed Elimam Ahamed Mohammed. Perceptions of undergraduate students about three 18- Yousif Elraih, Ismat H Ali, Mohammed E A Mohammed. Metformin and Sulfonylureas Effect on the Blood Level of prostate Specific Antigen. Asian Journal of Pharmaceutical and clinical Research 2015; 8(2); 247- 250.
- Mohammed Elimam Ahamed Mohammed, Khalid Abdelhafiz. Autoantibodies in the sera of breast cancer patients: Antinuclear and anti-double stranded DNA antibodies as example. Journal of Cancer Research and Therapeutics - April-June 2015 - Volume 11 - Issue 2; 341- 344.
- Eatimad Ali Abd Elhafise Babiker, Ahmed Elawad Elfaki, Mohammed Elimam Ahamed. Effect of Irradiation and Salting as Preservative Methods on Microbial Content of Red Sea Shrimp (Fenneropenaeus indicus). JOURNAL OF FOREST PRODUCTS & INDUSTRIES 2015, 4(3); 126-136.
- Brima, E. I., 5th International Chemistry Conference, King Khalid University, Abha, KSA. 26th – 29th April 2014. Poster: Determination of various Anions(Sulphate, Nitrate, Chloride, Fluoride) in Drinking Water by using Ion Chromatography.
- Brima, E. I., 5th International Chemistry Conference, King Khalid University, Abha, KSA. 26th – 29th April 2014. Poster: Investigation the Levels of Major and Trace Elements in Different Water Sources in Jeddah City.
- Brima, E. I., 5th International Chemistry Conference, King Khalid University, Abha, KSA. 26th – 29th April 2014. Poster: Determination of Citric Acid in Soft Drinks and Juice Drinks in Saudi Arabia.
- Brima, E. I., 5th International Chemistry Conference, King Khalid University, Abha, KSA. 26th – 29th April 2014. Poster: Application of Plasma-Assisted Ionisation (PAI) Mass Spectrometry (MS) to the Analysis of Volatiles in Vegetables and Fruits under Ambient Conditions.
- Brima, E. I., 5th International Chemistry Conference, King Khalid University, Abha, KSA. 26th – 29th April 2014. Poster: Arsenic Removal from Drinking Water by using Biomaterials & Prototype Filter.
- Brima, E. I., 5th International Chemistry Conference, King Khalid University, Abha, KSA. 26th – 29th April 2014. Oral: Plasma-Assisted Desorption Ionisation (PADI) Mass Spectrometry: A New Technique for Analysis of Pharmaceuticals, Polymers and Volatile Compounds.
- Brima, E. I., 5th International Chemistry Conference, King Khalid University, Abha, KSA. 26th – 29th April 2014. Oral: Comparison of different biomaterials for the removal of arsenic from drinking water.
- Brima, E. I., 10th Annual Scientific Research day , King Khalid University, Abha, KSA. 5th – 6th May 2014. Oral: Folic acid Measurement and Human Public Health; Review.
- Brima, E. I., Health and Safety Lecture, King Khalid University, Abha, Chemistry department.16th October 2014 Lecture.
- Brima, E. I., International Conference on the Marine Environment of the Red Sea (ICMERS). Faculty of Marine Sciences, King Abdulaziz University, Jeddah – Saudi Arabia. 10th – 13th November 2014. Poster: Determination of 28 Different Elements in Seaweed from the Red Sea as Bioindicator of Pollution Investigated using Inductively Coupled Plasma Mass Spectrometry.
- Brima, E. I., International Health Conference, 25th-27th June, 2015. Oxford, UK.Poster: Knowledge and Attitudes Towards Breastfeeding during Ramadan among women in Najran, Saudi Arabia.
- Brima, E. I., The 11th annual scientific research day 7th September 2015.Faculty of Sciences, Department of Chemistry. King Khalid university, Abha, KSA. Retrospective Studies in Methods for Water Treatment.
- Brima, E. I., First International Conference on Applied Chemistry (ICAC 2015)"Chemistry for Sustainable World"November 18- 19, 2015. Jeddah, KSA. Poster: Determination the levels of some essential elements in medicinal plants used in diabetes treatment by atomic absorption spectroscopy.
- Brima, E. I., First International Conference on Applied Chemistry (ICAC 2015)"Chemistry for Sustainable World"November 18- 19, 2015. Jeddah, KSA. Poster: Biomass materials used for removal of five elements from drinking water.
- Brima, E. I., First Saudi Conference on Environment on its main campus in Abha city, Aseer region – Kingdom of Saudi Arabia from 7th to 9th of March, 2016. Poster:Removal of lead from polluted wastewater by using different biomass materials.
- Brima, E. I., International Health Conference,Kings College London, 20th- 22nd June, 2016 London, UK. Oral: Toxic Elements in local tobacco (Shamma) and Cytological Changes in Oral Mucosa, Najran city, KSA.
- Brima, E. I., International Health Conference, St Hugh's College Oxford, 29th-June- 1st July, 2017. Oxford, UK. Oral: Essential and Toxic Elements in Different Medical Plants and Impact on humans Health. (accepted).
- M.E.A. MOHAMMED, The 5th International Chemistry Conference, 26-29 April 2014, Abha- KSA. Oral: Effect of FAC therapy on blood insulin concentration.
- M.E.A. MOHAMMED, The tenth research day, 2 May 2014, King Khalid University, Abha- KSA. Oral: Student performance in a seminar based examination.
- M.E.A. MOHAMMED, The fourth research day of the chemistry department, Dec 2014, King Khalid University, Abha- KSA. Oral: Effect of metformin and sulfonylureas of the blood PSA level.
- Eid Brima, Health and Safety Handbook, King Khalid University, KSA, 2016. English Version. ISBN:978-603-02-2512-5.
- Eid Brima, Health and Safety Handbook, King Khalid University, KSA, 2016 - Arabic Version. ISBN: 8-1323-02-603-978.
- Mohammed Elimam Ahamed Mohammed. Handbook of Basic Biochemistry. Science Publishing Group, New York 2016. ISBN 978-1- 940366-65-4.